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31st Advanced HLA Technical Workshop

March 12, 2017 – March 15, 2017
Omni La Costa Resort & Spa | Carlsbad, California
United States
English

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Join us in Carlsbad, California for the 31st Advanced HLA Technical Workshop. This program is led by a faculty of distinguished clinicians and scientists from the world-wide transplant community who will present lectures on the importance of assessing patient risk in transplantation, strategies for knowledge-based HLA antibody identification, and presentations on the role of HLA antibodies and NGS in bone marrow transplantation.  

This three-day workshop will also include presentations from the winners of the HLA case study competition which were just announced.



Event Information

Program

The 2017 Advanced HLA Technical Workshop in Carlsbad, California will include three morning sessions featuring cutting edge presentations in antibody monitoring and HLA genotyping. This year we are honored to have as our session moderators, Dr. Elaine Reed, Dr. Edgar Milford, and Dr. Dolly Tyan, three outstanding scientists who have helped to shape the field of HLA and Transplantation for more than 30 years. Their scientific accomplishments and global recognition will set the stage for a stimulating program.

This is a brief overview of the program. For a detailed view, please download the program.

 

MODERATORS:
 

Dr. Elaine Reed
Dr. Elaine Reed
University of California, Los Angeles
Los Angeles, CA

Dr. Edgar Milford
Dr. Edgar Milford
Harvard University
Boston, MA

Dr. Dolly Tyan
Dr. Dolly Tyan
Stanford University
Palo Alto, CA

 

Sunday — March 12

1:00 – 5:00 PM
Workshop Registration (Las Palmas)
6:00 – 9:00 PM
Welcome Cocktail & Dinner (Valley Promenade)

Monday — March 13 | Costa Del Sol D/E

8:00 AM
Introduction & Welcome
8:15 – 10:00 AM

Diagnosing Rejection in Solid Organ Transplantation

The role of antibodies in transplantation continues to dominate our field. While more and more research is being published, sorting through it all can be a challenge. Our session will give workshop participants an opportunity to better understand how innovation in antibody monitoring is truly moving the field of transplantation forward.

PRESENTATIONS:

The Antibody Phenotype: Looking beyond the MFI

Adriana Zeevi, PhD | University of Pittsburgh – Pittsburgh, PA

Dr. Adriana Zeevi will speak on the development of an anti-HLA antibody phenotype through multiple screening strategies.

The Molecular Phenotype: Molecular Microscope in the Clinic

Gaurav Gupta, MD | Virginia Commonwealth University - Richmond, VA

Dr. Alexandre Loupy will share the Paris integrative approach to disease diagnosis during his session.

Crunching the Numbers: Big Data in Transplantation

Alexandre Loupy, MD, PhD | Necker Hospital, Paris, France

Dr. Gaurav Gupta will provide a firsthand account of real-time clinical use of the Molecular Microscope, a new molecular gene expression assay, in his session.

10:00 – 10:30 AM
Coffee Break
10:30 AM - 12:30 PM

HLA Case Study Presentations

PANELISTS:
Donna Phelan, CHS | Barnes-Jewish Hospital -St. Louis, MO
Harriet Noreen | Fairview Hospital - Minneapolis, MN
PRESENTATIONS:

The Role of Donor-Specific Class II Anti-HLA Antibodies Detected by C1q in Humoral Rejection

Bobbie Rhodes-Clark, PhD | University of Arkansas for Medical Sciences – Little, AR

NGS of Small Bowel Biopsy Reveals Unresolved Donor Alleles and Eliminates Further Augmented Immunosuppression for AMR

Fiona (Fumiko) Yamamoto, BA, MS, CLS (CA) | Stanford Blood Center – Palo Alto, CA

Transplanting More Than a Pancreas; A Case Study

Jessica Jackstadt, B.S. MLS (ASCP)CM CHT (ABHI) | Albany Medical College – Albany, NY

DSA: True or False?

An Thi Truong Thai, MLS (ASCP)CM, CHS (ABHI) | Medstar Georgetown University Hospital – Washington, DC

Crossing DSA Barriers in Liver/Kidney Transplantation: We’re Not Out of the Woods Yet

Tracey Schilling, CHS | Johns Hopkins University – Baltimore, MD
12:30 - 5:00 PM
Free Afternoon

6:00 - 7:00 PM
EVENING SESSION

Meta-Analysis of Clinical Significance of Complement Activating Anti-HLA DSA in Kidney Transplantation

Alexandre Loupy, MD, PhD | Necker Hospital, Paris, France

Tuesday — March 14 | Costa Del Sol D/E

8:00 - 10:00 AM

Advancements in HLA Genotyping

As the field continues to advance, it can be difficult to keep up with the rapid pace of change. Our session will give attendees a moment to catch up and learn more about new developments in HLA genotyping.

PRESENTATIONS:

Combining Sanger SBT with Phasing Probes Results in Resolution of the Majority of HLA Variation

Carolyn Hurley, PhD | Georgetown University - Washington D. C.

Dr. Carolyn Hurley will open the session discussing how two existing technologies (SSO and SBT) can work harmoniously together to produce faster results with better resolution during her talk.
 

Making NGS a Reality – The University of Miami Experience

Phillip Ruiz, MD, PhD | University of Miami - Miami, FL

Dr. Philip Ruiz will discuss his experience with the implementation of NGS in his lab for clinical reporting during his presentation.
 

10:00 - 10:30 AM
Coffee Break

10:30 - 12:30 PM

Next Generation Sequencing Session

There are many new developments in HLA and Transplantation. This session will focus on advancements in HLA Genotyping in Bone Marrow and Solid Organ Transplantation.
PRESENTATIONS:

The NGS Era is Now!

Lee Ann Baxter Lowe, PhD | Children’s Hospital – Los Angeles, CA

Dr. Baxter-Lowe will explore the benefits of NGS and will lead the discussion detailing the accuracy, coverage, clinical relevance provided by NGS and consider the feasibility for small labs and discuss future directions.

NGS Implementation – Lessons Learned

Jennifer Zhang, PhD | UCLA - Los Angeles, CA

Dr. Zhang will continue the conversation sharing her experiences deploying NGS in the laboratory and review a number of interesting cases.

12:30 - 5:00 PM
Free Afternoon

6:00 - 7:00 PM
EVENING SESSION

Epitope Matching in Kidney Allocation: Is this the future?

Massimo Mangiola, PhD | University of Pittsburgh - Pittsburgh, PA
7:00 - 10:00 PM
Group Dinner (Valley Promenade / Legends Lawn)
 

Wednesday — March 15 | Costa Del Sol D/E

8:00 - 10:00 AM

The Impact of KAS: Are we Achieving Equity for the Highly Sensitized Candidate?

Robert Bray, PhD | Emory University – Atlanta, GA
Cathi Murphey, PhD | Southwest Immunodiagnostics - San Antonio, TX
10:00 - 10:30 AM
Coffee Break

10:30 - 12:30 PM

The REAL World: HLA Donor Typing Gets Real

Peter Lalli, PhD | Carolinas Health Care System - Charlotte, NC

Improving Virtual Crossmatching by Using Multiple Assay Platforms for Antibody Testing

Olga Timofeeva, PhD | Temple University - Philadelphia, PA
12:30 PM
Workshop Concludes