Literature References

Featured Publications

C1q-fixing human leukocyte antigen assay in immunized renal patients: correlation between Luminex SAB-C1q and SAB-IgG.

Llorente S, et al. | Transplant Proc. 2012 Nov.


There is no consensus about the impact of thresholds of complement-fixing antibody assays. Recently, a C1q-SAB assay has been developed to identify complement-fixing HLA...

Common and well-documented HLA alleles: 2012 update to the CWD catalogue.

Mack SJ, et al. | Tissue Antigens. 2013 Apr.


We have updated the catalogue of common and well-documented (CWD) human leukocyte antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele...

DSA-FXM: Accelerated donor specific flow crossmatch discriminating class I and II antibody specifically and only to donor HLA for determining true incompatibility.

Chen G, Lin L, Tyan DB | Transplantation. 2019 Aug.


We demonstrate that the DSA-FXM is able to define categorically distinct and clinically important HLA antibody profiles in half the time required for the standard FXM, potentially shortening cold ischemia time and providing clinicians with unambiguous essential information regarding HLA compatibility when time is critical.e have updated the catalogue of common and well-documented (CWD) human leukocyte antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele...

IgG Donor-Specific Anti-Human HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated Injury.

Lefaucheur C, et al. | J Am Soc Nephrol. 2016 Jan.


Antibodies may have different pathogenicities according to IgG subclass. We investigated the association between IgG subclasses of circulating anti-human HLA antibodies and...

Late Failing Heart Allografts: Pathology of Cardiac Allograft Vasculopathy and Association With Antibody-Mediated Rejection.

Loupy A, et al. | Am J Transplant. 2016 Jan.


We demonstrate that antibody-mediated rejection is operating in a substantial fraction of failing heart allografts and is associated with severe coronary arteriosclerosis...

Optimizing transplantation of sensitized heart candidates using 4 antibody detection assays to prioritize the assignment of unacceptable antigens

Reinsmoen NL, et al. | J Heart Lung Transplant. 2016 Feb.


Strategic prioritization of UA assignment has allowed transplantation of highly sensitized patients across the DSA barrier with survival rates comparable to DSA- heart transplant recipients...

The Molecular Microscope Diagnostic System (MMDx): Reading Human Biopsies Using mRNA Expression

One Lambda, Inc. | Brochure 2017 Sep.


Measuring mRNA in transplant biopsies | MMDx™ is a central diagnostic system that uses microarrays to measure mRNA levels in transplant biopsies ...

Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients

Keeshan BC, et al. | Clinical Transplantation 2017 Aug.


...To determine the clinical relevance of a positive FCXM in the context of negative CDCXM in heart transplantation, the United Network for Organ Sharing (UNOS) database was analyzed...