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C1q-fixing human leukocyte antigen assay in immunized renal patients: correlation between Luminex SAB-C1q and SAB-IgG.

Llorente S1, et al. | Transplant Proc. 2012 Nov.


There is no consensus about the impact of thresholds of complement-fixing antibody assays. Recently, a C1q-SAB assay has been developed to identify complement-fixing HLA...

Common and well-documented HLA alleles: 2012 update to the CWD catalogue.

Mack SJ, et al. | Tissue Antigens. 2013 Apr.


We have updated the catalogue of common and well-documented (CWD) human leukocyte antigen (HLA) alleles to reflect current understanding of the prevalence of specific allele...

IgG Donor-Specific Anti-Human HLA Antibody Subclasses and Kidney Allograft Antibody-Mediated Injury.

Lefaucheur C, et al. | J Am Soc Nephrol. 2016 Jan.


Antibodies may have different pathogenicities according to IgG subclass. We investigated the association between IgG subclasses of circulating anti-human HLA antibodies and...

Late Failing Heart Allografts: Pathology of Cardiac Allograft Vasculopathy and Association With Antibody-Mediated Rejection.

Loupy A, et al. | Am J Transplant. 2016 Jan.


We demonstrate that antibody-mediated rejection is operating in a substantial fraction of failing heart allografts and is associated with severe coronary arteriosclerosis...

Optimizing transplantation of sensitized heart candidates using 4 antibody detection assays to prioritize the assignment of unacceptable antigens

Reinsmoen NL, et al. | J Heart Lung Transplant. 2016 Feb.


Strategic prioritization of UA assignment has allowed transplantation of highly sensitized patients across the DSA barrier with survival rates comparable to DSA- heart transplant recipients...

The Molecular Microscope Diagnostic System (MMDx): Reading Human Biopsies Using mRNA Expression

One Lambda, Inc. | Brochure 2017 Sep.


Measuring mRNA in transplant biopsies | MMDx™ is a central diagnostic system that uses microarrays to measure mRNA levels in transplant biopsies ...

Value of a flow cytometry cross-match in the setting of a negative complement-dependent cytotoxicity cross-match in heart transplant recipients

Keeshan BC, et al. | Clinical Transplantation 2017 Aug.


...To determine the clinical relevance of a positive FCXM in the context of negative CDCXM in heart transplantation, the United Network for Organ Sharing (UNOS) database was analyzed...