Cytokine Genotyping

Researchers are currently investigating the role of cytokine expression levels in diseases such as cancer, AIDS, and autoimmune diseases. Cytokines are crucial in cellular communication and are key elements in controlling the immune response. Research suggests that polymorphic variants of cytokine genes may be associated with acute and chronic transplant rejection. These variants express the corresponding cytokine gene at either elevated or reduced levels. Expression levels of TGF-beta, TNF-alpha, IL-10, and IL-6 appear to affect the likelihood of organ rejection.1 Genotyping of these polymorphic variants might be used to further investigate the role of cytokines in organ transplants.

The Cytokine Genotyping tray provides an accurate, simple, and economical means of detecting polymorphisms of the following cytokine genes:

  • TGF-beta
    (Transforming Growth Factor - beta)
  • TNF-alpha
    (Tumor Necrosis Factor - alpha)
  • IL-10
    (Interleukin - 10)
  • IL-6
    (Interleukin - 6)
  • IFN-gamma
    (Interferon - gamma)

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Catalog #
Product Name
Cytokine Genotyping Tray
24 tests
Full Specification
HLA Class N/A
Product Name Cytokine Genotyping Tray
Format Micro SSP
Regulatory For Research Use Only. Not for use in diagnostic procedures.
Use A test assay for genotyping of specific cytokine factors.
Package Includes 4-DNA Primer Set Trays, Pre-aliquoted D-mix tubes, and Tray seals
Shipping Considerations Cold pack
Storage Temperature -20° C or below
Amount 24 tests
Technique SSP
Target Cytokine genes: TGF-beta, TNF-alpha, IL-10, IL-6, IFN-gamma

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